Catalog-specification

Delivery time

USD price

abs110765-50ul

In Stock

228

Overview

Description

A Rabbit Polyclonal Antibody (Pab) that has been purified through peptide affinity is available. To create new content related to the original text, the information can be rearranged.

Other names

Paired box protein Pax-8, PAX8ï¼›PAX8

Source

Rabbit

Specificity

The production of this PAX8 antibody involved immunizing rabbits with a synthetic peptide, which was conjugated to KLH. The peptide spanned amino acids 285-313 from the Central region of the human PAX8 protein. To create a similar content, the above information can be rearranged as follows:
Rabbits were immunized with a KLH-conjugated synthetic peptide derived from the Central region of the human PAX8 protein. This peptide corresponds to amino acids 285-313. By utilizing this approach, a PAX8 antibody with high specificity and affinity was successfully generated.

Species Reactivity

Human

Predictive reaction species

M

Application

WB~~1:1000
IHC-P~~1:10~50
FC~~1:10~50

Properties

Clonality

Polyclonal Antibody

Isotype

Rabbit Ig

Stability & Storage

To ensure optimal preservation, please keep the refrigerated temperature between 2-8°C for a maximum duration of 2 weeks. For extended storage, it is advisable to store the items at -20°C in small portions to prevent the negative effects of freeze-thaw cycles.

Storage buffer

This antibody is purified through peptide affinity purification followed by a protein A column to obtain a purified polyclonal antibody. It is supplied in PBS solution containing 0.09% (W/V) sodium azide as a preservative.

Research area

Neuroscience

Target

Background

One important regulator responsible for maintaining the unique gene expression profile in thyroid cells and preserving their functional identity is the transcription factor. It plays a crucial role in ensuring that only thyroid-specific genes are exclusively expressed in these cells, thereby supporting their specialized function. By orchestrating the intricate process of gene regulation, this transcription factor contributes significantly to the differentiation and proper functioning of thyroid cells.

Celluar localization

Nucleus.

UniPort

Q06710

References

References

Ramos,H.E., et.al., Thyroid 19 (1), 61-68 (2009)